hyperkeratosis$36729$ - definition. What is hyperkeratosis$36729$
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%ما هو (من)٪ 1 - تعريف

THICKENING OF THE STRATUM CORNEUM (THE OUTERMOST LAYER OF THE EPIDERMIS), OFTEN ASSOCIATED WITH THE PRESENCE OF AN ABNORMAL QUANTITY OF KERATIN
Plantar hyperkeratosis; Hyperkeratoses; Hyperkeratosis of the nipple and areola; Hyperkeratosis lenticularis perstans; Flegel's disease; Flegel disease; Hyperkeratosis lenticularis perstans of Flegel; Follicular hyperkeratosis; Follicular Hyperkeratosis; Hyperkeratotic; Hypokeratosis

hyperkeratosis         
[?h??p?k?r?'t??s?s]
¦ noun Medicine abnormal thickening of the outer layer of the skin.
Multiple minute digitate hyperkeratosis         
MEDICAL CONDITION
Digitate keratoses; Disseminated spiked hyperkeratosis; Familial disseminated piliform hyperkeratosis; Minute aggregate keratosis; Digitate keratosis
Multiple minute digitate hyperkeratosis (also known as "Digitate keratoses," "Disseminated spiked hyperkeratosis," "Familial disseminated piliform hyperkeratosis," and "Minute aggregate keratosis") is a rare cutaneous condition, with about half of cases being familial, inherited in an autosomal dominant fashion, while the other half are sporadic.
Epidermolytic hyperkeratosis         
RARE AND SEVERE FORM OF ICHTHYOSIS
Bullous congenital ichthyosiform erythroderma; Hyperkeratosis, epidermolytic; Congenital bullous ichthyosiform erythroderma; Bullous Ichthyosis; Epidermolytic hyperkeratosis (Bullous ichthyosiform erythroderma); Bullous ichthyosiform erythroderma; Epidermolytic palmoplantar keratoderma; EHK; Mosaic bullous congenital ichthyosiform erythroderma; Linear bullous ichthyosiform erythroderma; Epidermolytic ichthyosis
Epidermolytic ichthyosis (EI), also known as bullous epidermis ichthyosis (BEI), epidermolytic hyperkeratosis (EHK), bullous congenital ichthyosiform erythroderma (BCIE), bullous ichthyosiform erythrodermaFreedberg, et al. (2003).

ويكيبيديا

Hyperkeratosis

Hyperkeratosis is thickening of the stratum corneum (the outermost layer of the epidermis, or skin), often associated with the presence of an abnormal quantity of keratin, and also usually accompanied by an increase in the granular layer. As the corneum layer normally varies greatly in thickness in different sites, some experience is needed to assess minor degrees of hyperkeratosis.

It can be caused by vitamin A deficiency or chronic exposure to arsenic.

Hyperkeratosis can also be caused by B-Raf inhibitor drugs such as Vemurafenib and Dabrafenib.

It can be treated with urea-containing creams, which dissolve the intercellular matrix of the cells of the stratum corneum, promoting desquamation of scaly skin, eventually resulting in softening of hyperkeratotic areas.